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Systems Xcellence Announces Additional Client for its ASP Pharmacy Benefits Processing Service

Contract with U.S. PBM Continues Momentum for HxBenefit Inc. ASP Offering

MILTON, Ontario (December 13, 2000) -- Systems Xcellence Inc., (TSE: SXC) announced today that its wholly-owned subsidiary HxBenefit Inc., has signed a contract with the newest customer of its application service provider (ASP) offering. With this initial two year contract in place HxBenefit Inc. will provide pharmacy benefits processing services to a major U.S. Pharmacy Benefits Management (PBM) company. This agreement represents the most recent customer for HxBenefit and its application service offering, ClaimRx. Under the terms of the agreement, HxBenefit will supply its leading edge, full function, pharmacy benefit processing service and related Drug DecisionsT advanced reporting service, enabling the Customer to deliver effective and flexible healthcare benefit solutions to its customers.

HxBenefit Inc. will work with the Customer to migrate approximately 260,000 covered lives to the new service targeting a production implementation for 1st quarter of 2001. Over the next two years, the companies will work together to achieve a projected growth potential of 500,000 covered lives. HxBenefit will receive fees based on transactions that are processed through the ASP.

"This is exciting news as we welcome this important new customer. This contract continues our momentum as we attract new customers to our ASP offering through HxBenefit Inc. and continues to build our recurring revenue base. Both HxBenefit and SX staff are committed to our customer's success and we look forward to a strong and ongoing relationship," stated Gordon Glenn, President and CEO of Systems Xcellence.

"Our ClaimRx product offering combined with a talented team of industry professionals that understand the customer's needs providing our newest customer with the application services and support they require to grow their business," added Tim Rourke, Vice President HxBenefit Inc.

About the Customer:

This new Customer is a U.S. based Pharmacy Benefits Management (PBM) company servicing a diverse set of clients nationwide. HxBenefit was selected by the Customer to provide expanded and leading edge services to its existing clients representing approximately 260,000 covered lives and furthermore enables the customer to position itself for accelerated growth projected at 500,000 covered lives.

About HxBenefit Inc. and Systems Xcellence Inc.:

HxBenefit Inc. is an application service provider (ASP) focussed on the delivery of comprehensive pharmacy benefit processing and analysis services directly to Pharmacy Benefit Managers (PBMs), Managed Care Organizations (MCO's), retail pharmacies and other healthcare intermediaries involved in managing drug benefit programs. HxBenefit hosts the Systems Xcellence Inc. suite of Healthcare Xcellence (HX)T software as an application service provider (ASP), utilizing on-line transaction processing systems and the Internet. Customers have Internet portal-based access to the Company's rich and full function suite of products on a transaction or subscription fee basis. HxBenefit Inc. is located in its new data and operations center in Scottsdale, Arizona. HxBenefit Inc. can be found on the Internet at http://www.hxbenefit.com.

Systems Xcellence is headquartered in Milton, Ontario, and provides advanced online transaction processing solutions for the healthcare benefits management industry. The Company combines robust software products, business expertise, and services to deliver superior solutions to the ever-changing managed care sector. The Company's shares are traded on the Toronto Stock Exchange under the symbol SXC. Systems Xcellence can be found on the Internet at http://www.sxc.com.

For more information, please contact: Gordon Glenn, President and CEO
Systems Xcellence Inc.
Tel: (905) 876-4741

Email: investors@sx.com

Walt Ellenberger, Senior VP, Sales & Marketing
Systems Xcellence Inc.
Tel: (301) 947-5870

Email: ellenbw@sx.com