SYSTEMS XCELLENCE INC ANNOUNCES CLOSING OF $22.5 MILLION BOUGHT DEAL TREASURY OFFERING OF COMMON SHARES 

THIS NEWS RELEASE IS INTENDED FOR DISTRIBUTION IN CANADA ONLY AND IS NOT AUTHORIZED OR INTENDED FOR DISTRIBUTION TO UNITED STATES NEWSWIRE SERVICES OR FOR PUBLICATION OR DISSEMINATION IN THE UNITED STATES. 

MILTON, Ontario – November 29, 2005 - Systems Xcellence Inc. (“SXC” or the “Company”) today announced that it has successfully completed a bought deal public offering of 9,000,000 common shares at a price of $2.50 per common share for total gross proceeds of $22,500,000. All figures are in Canadian dollars. The common shares were sold by a syndicate of underwriters led by MGI Securities Inc. and included Versant Partners Inc., Clarus Securities Inc., Paradigm Capital Inc. and Blackmont Capital Inc.  The common shares are listed and posted for trading on the Toronto Stock Exchange.  SXC will use the proceeds from the offering for general corporate purposes and to support the Company’s growth initiatives.

About Systems Xcellence Inc.

Systems Xcellence (SXC) is headquartered in Milton, Ontario with offices and processing centres in Lombard, Illinois, Warminster, Pennsylvania, Scottsdale, Arizona and Victoria, British Columbia.  Through its SXC Health Solutions, Inc subsidiary, SXC is a leading provider of healthcare information technology solutions and services to the U.S. healthcare benefits management industry. The company’s product offerings and solutions combine a wide range of software applications, application service provider (ASP) processing services and professional services, designed for many of the largest organizations in the pharmaceutical supply chain, such as pharmacy benefit managers, managed care organizations, independent, chain and mail-order pharmacies and other healthcare intermediaries.  SXC can be found on the Internet at www.sxc.com. 

This press release contains forward-looking statements based on current expectations. These forward-looking statements entail various risks and uncertainties that could cause actual results to differ materially from those reflected in these forward-looking statements. Risks and uncertainties about the Company's business are more fully discussed in the Company's Annual Information Form.