SYSTEMS XCELLENCE TO HOST CONFERENCE CALL TO DISCUSS 2005 Third QUARTER RESULTS

Results to be released Thursday, November 3^rd at 7:00am

MILTON, Ontario – October 26, 2005, Systems Xcellence Inc., (TSX: SXC) announces that it will hold a conference call to discuss its 2005 third quarter financial results. Mr. Gordon Glenn, President and Chief Executive Officer will host the call. 

DATE:	Thursday, November 3, 2005
TIME:	8:30 am, Eastern Standard Time
WEBCAST:	A live audio webcast of the call will be available at www.sxc.com.   Webcast attendees are welcome to listen to the conference in real-time or on-demand at your convenience. The webcast will be archived for 360 days.   Please connect to this website at least 15 minutes prior to the conference call to ensure adequate time for any software download that may be needed to hear the webcast.
TAPED REPLAY:	A taped replay of the call will be available at 416-640-1917 or 1-877-289-8525. The reference number is 21159627. The replay will be available until November 10, 2005.

About Systems Xcellence Inc.

Systems Xcellence (SXC) is headquartered in Milton, Ontario with offices and processing centres in Lombard, Illinois, Warminster, Pennsylvania, Scottsdale, Arizona and Victoria, British Columbia.  Through its SXC Health Solutions, Inc subsidiary, SXC is a leading provider of healthcare information technology solutions and services to the U.S. healthcare benefits management industry. The company’s product offerings and solutions combine a wide range of software applications, application service provider (ASP) processing services and professional services, designed for many of the largest organizations in the pharmaceutical supply chain, such as pharmacy benefit managers, managed care organizations, independent, chain and mail-order pharmacies and other healthcare intermediaries. SXC can be found on the Internet at www.sxc.com.

This press release contains forward-looking statements based on current expectations. These forward-looking statements entail various risks and uncertainties that could cause actual results to differ materially from those reflected in these forward-looking statements. Risks and uncertainties about the Company's business are more fully discussed in the Company's Annual Information Form.